Secondary lymphedema can occur in anyone who has had treatment or injury that damages the lymphatic system. It primarily affects females and develops at puberty – but can appear without warning at any age – usually beginning with gradual swelling at the foot. Primary lymphedema is a hereditary condition that usually affects the lower extremities. Persistent swelling in the arm, leg, breast, abdomen, groin or head and neck.Unusual, unexplained tightness of clothing or jewelry in a specific area.
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